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GAD67 Polyclonal Antibody, 50ul Liquid Handling &Storage This gene is a member

SKU: 2096804937

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EUR185.00 EUR217.00

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GAD67 Polyclonal Antibody, 50ul Liquid Handling &Storage This gene is a memberGAD1 encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma aminobutyric acid from L glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin dependent diabetes. This gene may also play

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Description

This gene is a member of the SMCY homolog family and encodes a protein with one ARID domain

The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle

composed of three immunoglobulin-like domains

JUP encodes a major cytoplasmic protein (junction plakoglobin) which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions

It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators

GAD67 Polyclonal Antibody, 50ul Liquid Handling &Storage This gene is a memberGAD1 encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma aminobutyric acid from L glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin dependent diabetes. This gene may also play

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