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ENaC Gamma Polyclonal Antibody, 50ul Drug Development and Evaluation The Tn-I subunit inhibits actomyosin

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ENaC Gamma Polyclonal Antibody, 50ul Drug Development and Evaluation The Tn-I subunit inhibits actomyosinNonvoltage gated, amiloride sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. SCNN1G encodes the gamma subunit, and mutations in this gene have been associated with Liddle syndrome.

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Description

The Tn-I subunit inhibits actomyosin ATPase

The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state

a 70 kilodalton heat shock protein chaperone required for the proper folding and assembly of proteins in the ER

An important paralog of this gene is SLC30A4

or in an active form consisting solely of the mature peptide homodimer

ENaC Gamma Polyclonal Antibody, 50ul Drug Development and Evaluation The Tn-I subunit inhibits actomyosinNonvoltage gated, amiloride sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. SCNN1G encodes the gamma subunit, and mutations in this gene have been associated with Liddle syndrome.

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