Human Fibulin 5, FBLN5 ELISA Kit, 96T Custom DNA Oligos plays a central role in

plays a central role in diet induced thermogenesis: acts as a non-sympathetic brown fat (BAT) activator mediating prandial thermogenesis

Mutations in this gene are associated with Nijmegen breakage syndrome| an autosomal recessive chromosomal instability syndrome characterized by microcephaly| growth retardation| immunodeficiency| and cancer predisposition

Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP

Read-through transcription also exists between this gene and the downstream melanoma antigen family A

especially in brain development

Human Fibulin 5, FBLN5 ELISA Kit, 96T Custom DNA Oligos plays a central role inEssential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN (PubMed: 18185537). Stabilizes and organizes elastic fibers in the skin, lung and vasculature (By similarity). Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and