NAB2 Polyclonal Antibody, 50ul Primary Antibodies Involved in the PP6-mediated dephosphorylation

Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha

cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs)

This gene is found in a cluster of related genes on chromosome 11

Thought to form a receptor-activated non-selective calcium permeant cation channel

The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators

NAB2 Polyclonal Antibody, 50ul Primary Antibodies Involved in the PP6-mediated dephosphorylationNAB2 encodes a member of the family of NGFI A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo or hetero multimerize with other EGR or NAB proteins through a conserved N terminal domain, and repress transcription through two partially redundant C terminal domains. Transcriptional repression by the encoded protein is