Raf-1(Phospho Tyr341) Polyclonal Antibody, 20ul Inoculating Loops/Needles EphA6 (Hek12)

EphA6 (Hek12)

Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL)

The encoded protein functions as a scaffolding protein and plays roles in ubiquitination and transcription

Heterozygous loss-of-function mutations in KLF1 result in the dominant In (Lu) blood phenotype

RUFY1 (RUN and FYVE domain containing 1) encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain

Raf-1(Phospho Tyr341) Polyclonal Antibody, 20ul Inoculating Loops/Needles EphA6 (Hek12)This gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.