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JAK2 mouse Monoclonal Antibody(3F10), 50ul Micro Centrifuge Tubes Moesin is localized to filopodia

SKU: 20456295451

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JAK2 mouse Monoclonal Antibody(3F10), 50ul Micro Centrifuge Tubes Moesin is localized to filopodiaThis gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

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Description

Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement

The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme

Naturally-occurring readthrough transcription between this gene and upstream GeneID:147081 results in transcripts that encode isoforms that share similarity with the products of CRHR1

This receptor has various functions| including in the intracellular trafficking of lysosomal enzymes| the activation of transforming growth factor beta| and the degradation of insulin-like growth factor 2

CLIP2 is hemizygously deleted in Williams syndrome

JAK2 mouse Monoclonal Antibody(3F10), 50ul Micro Centrifuge Tubes Moesin is localized to filopodiaThis gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

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