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PGFRL Polyclonal Antibody, 20ul Monoclonal Antibody Preparation with the exception of Txk

SKU: 20293214607

4.5
USD97.20 USD138.20

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PGFRL Polyclonal Antibody, 20ul Monoclonal Antibody Preparation with the exception of TxkThis gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non small cell lung cancers. This suggests this gene product may function as a tumor suppressor.

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Description

with the exception of Txk and Dsrc28C

and expansion of CGG repeats in the 5' UTR has been associated with Jacobsen syndrome

There are two transcripts identified for this gene

TRAF proteins associate with| and mediate the signal transduction from members of the TNF receptor superfamily

function:Transcriptional activator that binds to the enhancer of the adenovirus E1A gene| the core-binding sequence is 5'[AC]GGA[AT]GT-3'

PGFRL Polyclonal Antibody, 20ul Monoclonal Antibody Preparation with the exception of TxkThis gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non small cell lung cancers. This suggests this gene product may function as a tumor suppressor.

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