FXR2 Polyclonal Antibody, 20ul sgRNA Oligos Defects in this gene are

Defects in this gene are a cause of mitochondrial pyruvate carrier deficiency

The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts

NOTCH2 encodes a member of the NOTCH family

Inactivating variants of this gene result in the recessive Lutheran null phenotype

Low affinity immunoglobulin gamma Fc region receptor II-b encoded by FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes

FXR2 Polyclonal Antibody, 20ul sgRNA Oligos Defects in this gene areThe protein encoded by FXR2 (FMR1 autosomal homolog 2) is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome.