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RSPH1 Polyclonal Antibody, 20ul Recombinant Protein Expression Experiments with knockout mice indicate

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RSPH1 Polyclonal Antibody, 20ul Recombinant Protein Expression Experiments with knockout mice indicateThis gene encodes a male meiotic metaphase chromosome associated acidic protein. This gene is expressed in tissues with motile cilia or flagella, including the trachea, lungs, airway brushings, and testes. Mutations in this gene result in primary ciliary dyskinesia 24. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Description

Experiments with knockout mice indicate that this gene attenuates

This gene encodes a CXXC-type zinc finger domain-containing protein that functions as an antagonist of the canonical wingless/integrated signaling pathway

function:Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells

controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation

This protein acts as a tumor suppressor by promoting ubiquitination and subsequent degradation of MDM2

RSPH1 Polyclonal Antibody, 20ul Recombinant Protein Expression Experiments with knockout mice indicateThis gene encodes a male meiotic metaphase chromosome associated acidic protein. This gene is expressed in tissues with motile cilia or flagella, including the trachea, lungs, airway brushings, and testes. Mutations in this gene result in primary ciliary dyskinesia 24. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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