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KCNK2 Rabbit Polyclonal Antibody, 100ul Recombinant Ab Production Members of the CELF/BRUNOL protein

SKU: 20028608449

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KCNK2 Rabbit Polyclonal Antibody, 100ul Recombinant Ab Production Members of the CELF/BRUNOL proteinThis gene encodes one of the members of the two pore domain background potassium channel protein family. This type of potassium channel is formed by two homodimers that create a channel that leaks potassium out of the cell to control resting membrane potential. The channel can be opened however by certain anesthetics membrane stretching intracellular acidosis and heat. Three transcript variants encoding different isoforms have been found for this gene.

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Description

Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains

is a 500 amino acid single-pass type I membrane protein that exists as two alternatively spliced isoforms

Interacts with REL

Overexpression of this gene has been associated with acute myelocytic leukemia

zymogen activation

KCNK2 Rabbit Polyclonal Antibody, 100ul Recombinant Ab Production Members of the CELF/BRUNOL proteinThis gene encodes one of the members of the two pore domain background potassium channel protein family. This type of potassium channel is formed by two homodimers that create a channel that leaks potassium out of the cell to control resting membrane potential. The channel can be opened however by certain anesthetics membrane stretching intracellular acidosis and heat. Three transcript variants encoding different isoforms have been found for this gene.

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