VATO Rabbit Polyclonal Antibody, 100ul Biomatrix The encoded protein can be

The encoded protein can be activated by proinflammatory cytokines and environmental stresses through phosphorylation by mitogen activated protein kinase kinases (MKKs)

including 2-5-oligoadenylate synthetase

and leumorphin

The protein encoded by this gene is found primarily in cerebellar Purkinje cells| where it functions as a protein phosphatase inhibitor

Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome

VATO Rabbit Polyclonal Antibody, 100ul Biomatrix The encoded protein can beThis gene encodes a portion of the V0 domain of vacuolar ATPase (V ATPase) a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Activity of this enzyme is necessary for such varied processes as protein sorting zymogen activation receptor mediated endocytosis and synaptic vesicle proton gradient generation. Alternative splicing results in multiple transcript variants.