Laminin Alpha-1 Polyclonal Antibody, 100ul In vitro Assessment Multiple pseudogenes on chromosome 9

Multiple pseudogenes on chromosome 9

Three transcript variants that encode two different protein isoforms have been described

The lipidated form migrates faster than its mature form on SDS-PAGE gel

Mutations in this gene are associated with the autosomal dominant disorder

MIM 609806) and ferrochelatase (FECH

Laminin Alpha-1 Polyclonal Antibody, 100ul In vitro Assessment Multiple pseudogenes on chromosome 9LAMA1 encodes one of the alpha 1 subunits of laminin. The laminins are a family of extracellular matrix glycoproteins that have a heterotrimeric structure consisting of an alpha, beta and gamma chain. These proteins make up a major component of the basement membrane and have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Mutations in this gene