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APOH Polyclonal Antibody, 50ul NGS Oligos The DNA-binding motifs suggest this

SKU: 19703311513

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APOH Polyclonal Antibody, 50ul NGS Oligos The DNA-binding motifs suggest thisApolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies

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Description

The DNA-binding motifs suggest this protein is involved in the regulation of transcription and chromatin remodeling

This protein controls cell cycle arrest and apoptosis by regulating p21| a cell cycle regulator| and the tumor suppressor protein p53

The protein encoded by IPPK (inositol-pentakisphosphate 2-kinase) is a kinase that phosphorylates position 2 of inositol-1

subcellular location:Enriched in lipid rafts

This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis

APOH Polyclonal Antibody, 50ul NGS Oligos The DNA-binding motifs suggest thisApolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies

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