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LTOR3 Polyclonal Antibody, 100ul Plates & Dishes GIMAP5 encodes GTPase IMAP family

SKU: 18931276388

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LTOR3 Polyclonal Antibody, 100ul Plates & Dishes GIMAP5 encodes GTPase IMAP familyThis gene encodes a scaffold protein that functions in the extracellular signal regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen activated protein binding protein interacting protein, and binds specifically to MAP kinase kinase MAP2K1 MEK1, MAP kinase MAPK3 ERK1, and MAP kinase MAPK1 ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation.

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Description

GIMAP5 encodes GTPase IMAP family member 5 belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins

and was shown to reduce cell growth in neuroblastoma cells

Signal transducer and activator of transcription 3 encoded by STAT3 is a member of the STAT protein family

was shown to inhibit beta-adrenergic receptor function in vitro

The protein encoded by this gene is one of the SSTRs

LTOR3 Polyclonal Antibody, 100ul Plates & Dishes GIMAP5 encodes GTPase IMAP familyThis gene encodes a scaffold protein that functions in the extracellular signal regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen activated protein binding protein interacting protein, and binds specifically to MAP kinase kinase MAP2K1 MEK1, MAP kinase MAPK3 ERK1, and MAP kinase MAPK1 ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation.

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