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TRIP6 Polyclonal Antibody, 20ul In vitro Assessment Synthesis of the encoded protein

SKU: 18736868653

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TRIP6 Polyclonal Antibody, 20ul In vitro Assessment Synthesis of the encoded proteinThis gene is a member of the zyxin family and encodes a protein with three LIM zinc binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA) dependent manner and it regulates LPA induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have

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Description

Synthesis of the encoded protein is inhibited by transforming growth factor beta-1

The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al

The hypusine modification increases the interaction with XPO4

B-cell linker bridges B cell receptor-associated kinase activation with downstream signaling pathways

it has been demonstrated that the protein actually has protein disulfide isomerase activity

TRIP6 Polyclonal Antibody, 20ul In vitro Assessment Synthesis of the encoded proteinThis gene is a member of the zyxin family and encodes a protein with three LIM zinc binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA) dependent manner and it regulates LPA induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have

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