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c-Abl(Phospho-Tyr412) Rabbit Polyclonal Antibody, 50ul Protein Research Serine/threonine-protein kinase SNF1-like kinase 2

SKU: 18569222960

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c-Abl(Phospho-Tyr412) Rabbit Polyclonal Antibody, 50ul Protein Research Serine/threonine-protein kinase SNF1-like kinase 2This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes including cell division adhesion differentiation and response to stress. The activity of the protein is negatively regulated by its SH3 domain whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA binding activity that is regulated by CDC2 mediated phosphorylation suggesting a

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Description

Serine/threonine-protein kinase SNF1-like kinase 2 (SIK) phosphorylates Ser-794 of IRS1 in insulin-stimulated adipocytes

Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms

With the ability to store at 2-8℃ for maximum stability

This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1)| which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis

is a multiprotein complex composed of at least ten nonidentical subunits

c-Abl(Phospho-Tyr412) Rabbit Polyclonal Antibody, 50ul Protein Research Serine/threonine-protein kinase SNF1-like kinase 2This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes including cell division adhesion differentiation and response to stress. The activity of the protein is negatively regulated by its SH3 domain whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA binding activity that is regulated by CDC2 mediated phosphorylation suggesting a

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