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XRCC3 Polyclonal Antibody, 100ul[BT-AP09626] Dry Bath A chromosomal translocation and gene

SKU: 18368974709

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XRCC3 Polyclonal Antibody, 100ul[BT-AP09626] Dry Bath A chromosomal translocation and geneXRCC3 encodes a member of the RecA Rad51 related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair deficient mutant that exhibits hypersensitivity to a number of different DNA damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying

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Description

A chromosomal translocation and gene fusion between this gene and zinc finger| MIZ-type containing 1 (Gene ID: 57178) may underlie intellectual disability and neuropsychiatric problems in a human patient

The encoded protein contains one homeobox and nine zinc finger domains

GO annotations related to this gene include actin binding and kinesin binding

located on chromosomes 7 and 13

but not to the corresponding alcohols

XRCC3 Polyclonal Antibody, 100ul[BT-AP09626] Dry Bath A chromosomal translocation and geneXRCC3 encodes a member of the RecA Rad51 related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair deficient mutant that exhibits hypersensitivity to a number of different DNA damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying

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