AMMR1 Rabbit Polyclonal Antibody, 50ul Diagnostic Probes & Oligos Contains 1 PLAT domain

Contains 1 PLAT domain

Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells

Mutations in ZAP70 cause selective T-cell defect

and other polypeptides

conserved DNA elements (heat shock elements or HSEs) and CCAAT boxes

AMMR1 Rabbit Polyclonal Antibody, 50ul Diagnostic Probes & Oligos Contains 1 PLAT domainThe exact function of this gene is not known, however, submicroscopic deletion of the X chromosome including this gene, COL4A5, and FACL4 genes, result in a contiguous gene deletion syndrome, the AMME complex (Alport syndrome, mental retardation, midface hypoplasia, and elliptocytosis). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.