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RCC1 Polyclonal Antibody, 50ul Vortex Mixer in cells undergoing apoptosis

SKU: 18060244040

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RCC1 Polyclonal Antibody, 50ul Vortex Mixer in cells undergoing apoptosisThe Ras family small GTPase Ran is involved in nuclear envelope formation, assembly of the mitotic spindle and nuclear transport. Like other small GTPases, Ran is active in its GTP bound form and inactive in its GDP bound form. Nuclear RanGTP concentration is maintained through nuclear localization of guanine nucleotide exchange factor (GEF) activity, which catalyzes the exchange of bound GDP for GTP. RCC1 (regulator of chromatin condensation 1) is

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Description

in cells undergoing apoptosis

This gene encodes a subunit of the Integrator complex which is involved in the cleavage of small nuclear RNAs U1 and U2 within the nucleus

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and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome

In the autosomal dominant form

RCC1 Polyclonal Antibody, 50ul Vortex Mixer in cells undergoing apoptosisThe Ras family small GTPase Ran is involved in nuclear envelope formation, assembly of the mitotic spindle and nuclear transport. Like other small GTPases, Ran is active in its GTP bound form and inactive in its GDP bound form. Nuclear RanGTP concentration is maintained through nuclear localization of guanine nucleotide exchange factor (GEF) activity, which catalyzes the exchange of bound GDP for GTP. RCC1 (regulator of chromatin condensation 1) is

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