BRCA1 Polyclonal Antibody, 50ul[BT-AP00968] sgRNA Oligos SERPIND1 encodes a plasma serine

SERPIND1 encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor

and is found to be activated by sphingosine 1-phosphate

which results in the activation of several signaling cascades

This particular gene maps to chromosome X in a head-to-head orientation with SPANX family member A2| which appears to be a duplication of the A1 locus

A chromosomal rearrangement resulting in the expression of a fusion gene containing a portion of this gene and the intracellular kinase-encoding domain of the ret proto-oncogene is the cause of thyroid papillary carcinoma

BRCA1 Polyclonal Antibody, 50ul[BT-AP00968] sgRNA Oligos SERPIND1 encodes a plasma serineBRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein (BRCA1, DNA repair associated) combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal