MLCK(Phospho Tyr471) Rabbit Polyclonal Antibody, 50ul Centrifugal Filter Alternatively spliced transcript variants differing

Alternatively spliced transcript variants differing only in their 5' UTRs have been found for this gene

Hirschsprung disease

Mutations in this gene may cause adolescent onset distal myopathy

DHX8 is a member of the DEAH box polypeptide family

The level of expression is regulated by glucocorticoids

MLCK(Phospho Tyr471) Rabbit Polyclonal Antibody, 50ul Centrifugal Filter Alternatively spliced transcript variants differingThis gene a muscle member of the immunoglobulin gene superfamily encodes myosin light chain kinase which is a calcium calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition using a separate promoter in an intron in the 3' region it encodes telokin a small protein