ApoC-III Polyclonal Antibody, 50ul Petri Dishes Essential cofactor that acts via

Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1

tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity

Alternative splicing results in multiple transcript variants encoding multiple isoforms

Extracts misfolded glycoproteins

Defects in this gene are a cause of childhood cancer retinoblastoma (RB)| bladder cancer| and osteogenic sarcoma

ApoC-III Polyclonal Antibody, 50ul Petri Dishes Essential cofactor that acts viaApolipoprotein C III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A I and A IV genes are transcribed from the same strand, while the A 1 and C III genes are convergently transcribed. An increase in apoC III levels induces the development of