SRGP1 Rabbit Polyclonal Antibody, 50ul Vacuum Aspirator Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified

It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage

There are two transcirpts variants in mRNA level

MAP kinase kinase kinase subfamily

It heteromultimerizes with another MAGUK protein

SRGP1 Rabbit Polyclonal Antibody, 50ul Vacuum Aspirator Multiple alternatively spliced transcript variantsThe protein encoded by this gene is a GTPase activator working with the GTPase CDC42 to negatively regulate neuronal migration. The encoded protein interacts with the transmembrane receptor ROBO1 to inactivate CDC42.