PIAS 3 Polyclonal Antibody, 20ul Peptide Library Among its related pathways are

Among its related pathways are Prostate Cancer and B Cell Receptor Signaling Pathway (WikiPathways)

Several pseudogenes of EIF4E are found on other chromosomes

It is a member of the group-II aristaless-related protein family whose members are expressed primarily in the central and/or peripheral nervous system

Mutations in this gene cause Leigh syndrome due to mitochondrial complex I deficiency

Promotes integrin alpha-5/beta-1 and fibronectin (FN) matrix assembly in breast cancer cells

PIAS 3 Polyclonal Antibody, 20ul Peptide Library Among its related pathways arePIAS3 encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. Protein inhibitor of activated STAT 3 functions as a SUMO (small ubiquitin like modifier) E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity.