Collagen II alpha 1 (Cleaved-Ala1241) Rabbit Polyclonal Antibody, 20ul sgRNA Oligos Catalytic activity:Ubiquitin C-terminal thioester +

Catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol

This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain

and is overexpressed in the brain of Down syndrome fetuses

Sumoylation inhibits the AP-1 transcriptional activity and is| itself| inhibited by Ras-activated phosphorylation on Thr-232

This gene is part of a cluster of cytochrome P450 genes on chromosome 19

Collagen II alpha 1 (Cleaved-Ala1241) Rabbit Polyclonal Antibody, 20ul sgRNA Oligos Catalytic activity:Ubiquitin C-terminal thioester +disease: Defects in COL2A1 are a cause of primary avascular necrosis of femoral head (ANFH)