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PP4R1 Polyclonal Antibody, 50ul Adeno-associated Virus Packaging and have a critical role

SKU: 16264473923

4.2
SEK185.00 SEK205.00

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PP4R1 Polyclonal Antibody, 50ul Adeno-associated Virus Packaging and have a critical roleThis gene encodes one of several alternate regulatory subunits of serine threonine protein phosphatase 4 (PP4). The protein features multiple HEAT repeats. This protein forms a complex with PP4RC. This complex may have a distinct role from other PP4 complexes, including regulation of HDAC3 (Zhang et al., PMID: 15805470). There is also a transcribed pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants.

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Description

and have a critical role in the maturation of

Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration

this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter

May also be involved in the regulation of gene expression

An allelic polymorphism in FCGR2C results in both coding and non-coding variants

PP4R1 Polyclonal Antibody, 50ul Adeno-associated Virus Packaging and have a critical roleThis gene encodes one of several alternate regulatory subunits of serine threonine protein phosphatase 4 (PP4). The protein features multiple HEAT repeats. This protein forms a complex with PP4RC. This complex may have a distinct role from other PP4 complexes, including regulation of HDAC3 (Zhang et al., PMID: 15805470). There is also a transcribed pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants.

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