NFKappaB-p65 Polyclonal Antibody, 50ul[BT-AP05998] Metabolic enzymes tool compounds Mutations in this gene are

Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A

Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid

Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis

In adult liver

lymphocyte development and proliferation

NFKappaB-p65 Polyclonal Antibody, 50ul[BT-AP05998] Metabolic enzymes tool compounds Mutations in this gene areNF kappa B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF kappa B moves to the nucleus and activates transcription of specific genes. NF kappa B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF kappa B is NFKB1 complexed with the product of this gene, RELA. Four