Rb Polyclonal Antibody, 100ul[BT-AP07694] Electrophoresis & Labeling Mutations in this gene are

Mutations in this gene are associated with Hermansky-Pudlak syndrome type 6

subcellular location:Seems to be excluded from nucleoli

These disorders have at least 14 complementation groups

Two protein-coding transcripts and one non-protein coding transcript have been found for this gene

this kit measures IL-1α levels in human samples

Rb Polyclonal Antibody, 100ul[BT-AP07694] Electrophoresis & Labeling Mutations in this gene areThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.