MKP-2 Polyclonal Antibody, 50ul Dry Bath IGF2R encodes a receptor for

IGF2R encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate

A soluble form

on the same chromosome several hundred kilobases away (PMID: 21336277 and 22928559)

A germline mutation of this gene is the basis of familial inheritance of VHL syndrome

this interaction leads to a cooperativity between the two proteins in DNA binding

MKP-2 Polyclonal Antibody, 50ul Dry Bath IGF2R encodes a receptor forThe dual specificity phosphatase 4 encoded by DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine threonine and phosphotyrosine residues. They negatively regulate members of the mitogen activated protein (MAP) kinase superfamily (MAPK ERK, SAPK JNK, p38), which are associated with cellular proliferation and differentiation. Different