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RGPA1 Polyclonal Antibody, 20ul Serum & Sample Tubes Globin gene expression is regulated

SKU: 14490724477

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RGPA1 Polyclonal Antibody, 20ul Serum & Sample Tubes Globin gene expression is regulatedThis gene encodes a major subunit of the RAL GTPase activating protein. A similar protein in mouse binds E12, a transcriptional regulator of immunoglobulin genes. The mouse protein also functions in skeletal muscle by binding to the regulatory 14 3 3 proteins upon stimulation with insulin or muscle contraction. A pseudogene of this gene has been identified on chromosome 9.

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Description

Globin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha- and beta-gene clusters (summarized by Blank et al

The BAGE family was expanded by juxtacentromeric movement and/or acrocentric exchanges

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors

This protein may also play a role in early development

Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM)

RGPA1 Polyclonal Antibody, 20ul Serum & Sample Tubes Globin gene expression is regulatedThis gene encodes a major subunit of the RAL GTPase activating protein. A similar protein in mouse binds E12, a transcriptional regulator of immunoglobulin genes. The mouse protein also functions in skeletal muscle by binding to the regulatory 14 3 3 proteins upon stimulation with insulin or muscle contraction. A pseudogene of this gene has been identified on chromosome 9.

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