HPS5 Polyclonal Antibody, 50ul Plasma Transcription factor required for TBX21/T-bet-dependent

Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression

Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates| and may lead to Zellweger syndrome| severe mental retardation| and death in children

ALDH1B1 does not contain introns in the coding sequence

a glycine/phenylalanine (G/F)-rich region

Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP)

HPS5 Polyclonal Antibody, 50ul Plasma Transcription factor required for TBX21/T-bet-dependentThis gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky Pudlak syndrome 6 protein and may interact with the cytoplasmic domain of integrin, alpha 3. Mutations in this gene are associated with Hermansky Pudlak syndrome type 5. Multiple transcript variants encoding two distinct isoforms have been identified for this gene.