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P53 (Mono Methyl Lys370) Monoclonal Antibody(Q59), 20ul Culture Plate Inserts T cell activation was reported

SKU: 13706479175

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P53 (Mono Methyl Lys370) Monoclonal Antibody(Q59), 20ul Culture Plate Inserts T cell activation was reportedThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss

GUF1 (GUF1 GTPase)

It is a mediator of mitochondrial damage induced by caspase-8 (CASP8)| CASP8 cleaves this encoded protein

overexpression

SEMA3A is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain

P53 (Mono Methyl Lys370) Monoclonal Antibody(Q59), 20ul Culture Plate Inserts T cell activation was reportedThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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