TBX10 Polyclonal Antibody, 50ul Yeast Expression GlcNAcalpha1-->4Galbeta-->R and is largely associated

GlcNAcalpha1-->4Galbeta-->R and is largely associated with the Golgi apparatus membrane

Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling

which participates in the initiation of translation by aiding in the recruitment of protein and mRNA components to the 40S ribosome

Alternatively spliced transcripts encoding different isoforms have been identified for this gene

Binding of tepidermal growth factor receptor to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation

TBX10 Polyclonal Antibody, 50ul Yeast Expression GlcNAcalpha1-->4Galbeta-->R and is largely associatedTBX10 encodes a member of the T box family of transcription factors. These transcription factors share a DNA binding domain called the T box, and play a role in several developmental processes including early embryonic cell fate and organogenesis. The encoded protein is a member of the T box 1 subfamily. Mutations in this gene are thought to be a cause of isolated cleft lip with or without cleft palate.