PAR4 Polyclonal Antibody, 20ul[BT-AP12783] Pathway and Network Analysis Mutations in this gene have

Mutations in this gene have been associated with Aicardi-Goutieres syndrome

The encoded protein plays a role in cell-cycle progression and spindle organization

The 5' portion of this gene and two neighboring cytochrome p450 genes are included in a deletion that results in an autosomal-dominant form of nonsyndromic optic nerve aplasia (ONA)

This gene encodes a member of the P-type lectin family

GATA6 is a member of a small family of zinc finger transcription factors that play an important role in the regulation of cellular differentiation and organogenesis during vertebrate development

PAR4 Polyclonal Antibody, 20ul[BT-AP12783] Pathway and Network Analysis Mutations in this gene haveThe tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1 interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.