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ACTR-IC Polyclonal Antibody, 100ul Deep Well Plates The thrombospondin type 1 repeat

SKU: 12727419112

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ACTR-IC Polyclonal Antibody, 100ul Deep Well Plates The thrombospondin type 1 repeatACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al. 2001 [PubMed 12063393]).

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Description

The thrombospondin type 1 repeat domain is found in many proteins with diverse biological functions including cellular adhesion

Mutations in this gene have been associated with various ciliopathies

and skin atrophy) seen in CRF

SLC52A2 (solute carrier family 52 member 2) encodes a membrane protein which belongs to the riboflavin transporter family

and that binding is enhanced when cytokeratins 8 and 18 are present

ACTR-IC Polyclonal Antibody, 100ul Deep Well Plates The thrombospondin type 1 repeatACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al. 2001 [PubMed 12063393]).

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