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5-LO Polyclonal Antibody, 100ul Cell Proliferation Studies of the mouse counterpart

SKU: 12674362645

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5-LO Polyclonal Antibody, 100ul Cell Proliferation Studies of the mouse counterpartALOX5 encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The arachidonate 5 lipoxygenasen, which is expressed specifically in bone marrow derived cells, catalyzes the conversion of arachidonic acid to 5(S) hydroperoxy 6 trans 8,11,14 cis eicosatetraenoic acid, and further to the allylic epoxide 5(S) trans 7,9 trans 11,14 cis eicosatetrenoic acid (leukotriene A4). Leukotrienes

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Description

Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis

RCBTB1 (RCC1 and BTB domain containing protein 1) encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex

Mutations in this gene are associated with defects in organ development

Interacts with MLLT3

while expression is weak to moderate in astrocytomas

5-LO Polyclonal Antibody, 100ul Cell Proliferation Studies of the mouse counterpartALOX5 encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The arachidonate 5 lipoxygenasen, which is expressed specifically in bone marrow derived cells, catalyzes the conversion of arachidonic acid to 5(S) hydroperoxy 6 trans 8,11,14 cis eicosatetraenoic acid, and further to the allylic epoxide 5(S) trans 7,9 trans 11,14 cis eicosatetrenoic acid (leukotriene A4). Leukotrienes

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