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HLA-DO Alpha Polyclonal Antibody, 50ul Multiplex Immunoassays This protein is a component

SKU: 12501162807

4.1
USD162.00 USD201.00

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HLA-DO Alpha Polyclonal Antibody, 50ul Multiplex Immunoassays This protein is a componentHLA DOA belongs to the HLA class II alpha chain paralogues. HLA DOA forms a heterodimer with HLA DOB. The heterodimer, HLA DO, is found in lysosomes in B cells and regulates HLA DM mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.

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Description

This protein is a component of anaphase-promoting complex (APC)

Pseudogenes associated with this gene have been identified and are located on chromosome 15

A protein encoded by this human locus has been found to localize to pre-mRNA splicing complexes in the nucleus and is necessary for pre-mRNA splicing

Contains 1 BTB (POZ) domain

cell migration

HLA-DO Alpha Polyclonal Antibody, 50ul Multiplex Immunoassays This protein is a componentHLA DOA belongs to the HLA class II alpha chain paralogues. HLA DOA forms a heterodimer with HLA DOB. The heterodimer, HLA DO, is found in lysosomes in B cells and regulates HLA DM mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.

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