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CKR-5 Polyclonal Antibody, 20ul[BT-AP14980] Pathway and Network Analysis Two alternatively spliced transcript variants

SKU: 12459891292

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CKR-5 Polyclonal Antibody, 20ul[BT-AP14980] Pathway and Network Analysis Two alternatively spliced transcript variantsThis gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co receptor for macrophage tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include

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Description

Two alternatively spliced transcript variants encoding the same protein

Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB)

KRAS (KRAS proto-oncogene

Further processing of the beta subunit results in the formation of the M10 peptide| which has been shown to reduce lung fibrosis

an autosomal dominant pre-malignant disease that usually progresses to malignancy

CKR-5 Polyclonal Antibody, 20ul[BT-AP14980] Pathway and Network Analysis Two alternatively spliced transcript variantsThis gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co receptor for macrophage tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include

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