PA26 Polyclonal Antibody, 20ul Cellular Cultivation & Health Management Three transcript variants encoding two

Three transcript variants encoding two different isoforms have been found for this gene

This protein is implicated in the regulation of mRNA stability

Mutations in TP53 are associated with a variety of human cancers

In response to stress

The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands

PA26 Polyclonal Antibody, 20ul Cellular Cultivation & Health Management Three transcript variants encoding twoSESN1 encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The sestrin 1 mediates p53 inhibition of cell growth by activating AMP activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized