COP1(Phospho Ser387) Polyclonal Antibody, 100ul Bottles In addition to chromosomal rearrangement

In addition to chromosomal rearrangement

Disruption of LIG1 may also be associated with a variety of cancers

A similar protein in mouse plays a role in both interkinetic nuclear migration

Processed forms MDC(3-69)| MDC(5-69) and MDC(7-69) seem not be active

The encoded protein may play a role in apoptosis in a caspase-dependent manner

COP1(Phospho Ser387) Polyclonal Antibody, 100ul Bottles In addition to chromosomal rearrangementThe RING finger domain, in addition to its role in ubiquitination, functions as a structural scaffold to bring two clusters of positive charged residues within spatial proximity to mimic a bipartite nuclear localization signal (NLS).,E3 ubiquitin protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin conjugating enzyme in the form of a thioester