HDAC7 Polyclonal Antibody, 50ul Immune Repertoire Sequencing Several transcript variants encoding different

Several transcript variants encoding different isoforms have been found for CLNS1A

This gene is induced during apoptosis

Pseudogenes of this gene have been defined on chromosomes 1 and 8

The mouse ortholog of this protein has been characterized and has a domain structure of an N-terminal signal peptide| glycosidase domain| transmembrane domain| and a short cytoplasmic tail

Disruptions in this gene are associated with Duchenne muscular dystrophy

HDAC7 Polyclonal Antibody, 50ul Immune Repertoire Sequencing Several transcript variants encoding differentHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 7 encoded by HDAC7 has sequence homology to members of the histone deacetylase family. HDAC7 is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT.