Flk-1 Polyclonal Antibody, 50ul[BT-AP03269] Sealing Film This protein is located in

This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA

May play a role in the regulation of the immune system

Mutations in TRIP4 are associated with spinal muscular atrophy with congenital bone fractures-1 (SMABF1)

Studies of the orthologous mouse protein indicate that it functions in kidney development by promoting nephron progenitor differentiation| and it also functions in the development of the retina and optic chiasm

200 residues at the N-terminus (domains IV

Flk-1 Polyclonal Antibody, 50ul[BT-AP03269] Sealing Film This protein is located inVEGF R1 is one of the five receptor tyrosine kinases (RTKs) (Flt 1, KDR Flk 1, Flt 4, tie 1, and tek tie 2) whose expression is almost exclusively restricted to the endothelial cells. Tie 1 and tek tie 2 define a new class of RTKs containing two immunoglobulin like domains, three EGF homology domains and three fibronectin type III domains in their extracellular regions. Flt 1, KDR Flk 1 and Flt 4 are members of the class III subfamily of RTKs