GLRX1 Polyclonal Antibody, 50ul Human Genome Knockout Libraries The active subunit Bb is

The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase

Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA)

Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted

The encoded protein is a type 1 single Ig domain orphan receptor localized to the alpha-granule membranes of platelets

Aberrant expression of this gene is associated with type 2 diabetes and cancer progression in several cell types

GLRX1 Polyclonal Antibody, 50ul Human Genome Knockout Libraries The active subunit Bb isThis gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S glutathionylation status of signalling mediators. It is involved in beta amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced