CKLF7 Polyclonal Antibody, 50ul Bottles CABLES1 encodes a protein (Cdk5

CABLES1 encodes a protein (Cdk5 and Abl enzyme substrate 1) involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases

Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains

Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported| with the most common allele| Ile654/Ile655| shown here

NF-kappa-B heterodimeric RelB-p50 and RelB-p52 complexes are transcriptional activators

50mLx15pcs

CKLF7 Polyclonal Antibody, 50ul Bottles CABLES1 encodes a protein (Cdk5This gene belongs to the chemokine like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine like factor genes located in a cluster on chromosome 3. This gene acts as a tumor suppressor that regulates G1 S transition in the cell cycle, and epidermal growth factor receptor protein kinase B signaling during tumor pathogenesis. Alternative splicing results in