Syk(Phospho Tyr323) Polyclonal Antibody, 20ul Lentiviral Packaging providing improved sensitivity

providing improved sensitivity

The protein encoded by LAT (linker for activation of T-cells) is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway

The encoded protein also plays a prominent role in the activation of the Notch signaling pathway

Mitogenic stimulation leads to binding and activation of a complex composed of FRAP1 and RAPTOR

Mutations in this gene result in autosomal recessive spastic paraplegia

Syk(Phospho Tyr323) Polyclonal Antibody, 20ul Lentiviral Packaging providing improved sensitivityThis gene encodes a member of the family of non receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas.