PTPRB Polyclonal Antibody, 20ul Antibodies subcellular location:Associated with CD180 at

subcellular location:Associated with CD180 at the cell surface

The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils

Translocates from cytoplasm to nucleus under dexamethasone induction

Polymorphisms in this gene have been linked to breast and prostate cancer

Some of these associations were further supported by gene expression analyses and an association study in essential hypersomnia (EHS)

PTPRB Polyclonal Antibody, 20ul Antibodies subcellular location:Associated with CD180 atThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP