Mouse Osteopontin, OPN ELISA Kit, 96T Protein Post-translational Modification and farnesylation of the protein

and farnesylation of the protein is required for this activity

Two transcript variants that encode different isoforms have been found for this gene

and the second one lacks the essential Glu active site residue at position 889

Belongs to the tenascin family

is essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs

Mouse Osteopontin, OPN ELISA Kit, 96T Protein Post-translational Modification and farnesylation of the proteinMajor non collagenous bone protein that binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell matrix interaction. Acts as a cytokine involved in enhancing production of interferon gamma and interleukin 12 and reducing production of interleukin 10 and is essential in the pathway that leads to type I immunity.