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Culture of Murine Hippocampal Neuronal Cell Line HT22 The HT22 cell line was purchased from Shanghai Hongshun Biologicals (China) and maintained in high-glucose DMEM supplement with 10% FBS, 100 U/ml penicillin, and 100 g/ml streptomycin

Hepatocyte growth factor (HGF) is the high-affinity ligand for Mesenchymal Epithelial Transition Factor (c-Met), which belongs to the tyrosine kinase receptor family and is predominantly expressed in epithelial cells

The enrichment of S-palmitoylation sites at the C-terminal region of ATG2A suggests that S-palmitoylation may facilitate the anchoring of the C-terminus to the ER membrane

The 10 structural models with the lowest associated energy from 100 calculated structural models were used to prepare figures using the PyMOL Molecular Graphics System, Version 2.4 (Schrdinger, LLC)