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Histopathological variants of Hashimoto thyroiditis have been described, including: Atrophic and fibrotic variants Riedel thyroiditis Immunoglobulin G4 (IgG4)-related thyroiditis Radionuclide Scanning (RAIU) Early stages: Increased uptake Late stages: Low or absent uptake May show a heterogeneous pattern Gadolinium-67 scan: Can identify increased uptake in suspected thyroid lymphoma CT/MRI Imaging CT scan: Diffuse enlargement

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While the test is designed to inform GLP-1 and peptide-based treatment decisions, variants affecting glutathione synthesis or detoxification can be interpreted with a qualified provider to support discussions about complementary nutritional or supplemental approaches

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