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In the UK, hydroxocobalamin 1 mg intramuscular injection is used: Without neurological involvement : 1 mg three times weekly for two weeks, then maintenance of 1 mg every two to three months With neurological involvement : 1 mg on alternate days until no further improvement in symptoms, then maintenance of 1 mg every two months Lifelong maintenance is required for pernicious anaemia or other irreversible causes of deficiency Oral B12 supplementation may be appropriate for diet-related deficiency in patients without neurological symptoms and with adequate absorption capacity

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Providers can also combine B12 with vitamin C, magnesium, zinc, glutathione, and B-complex vitamins in a single session, making infusions a more versatile option for severe deficiency, athletic recovery, illness recovery, and chronic fatigue

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Build injection into an existing morning routine

Nausea: Consider taking this medicine after meals to lessen this effect